JIGYASA Study

(Joint Initiative for Genomic risk stratification by Yern Asians to fight heart disease in South Asians)

Jigyasa means curiosity to know things. At present, the guidelines on when to get a heart calcium scan do not account for people of South Asian descent. If we can determine at what age someone should get a heart calcium scan, we can optimize health care resource use to identify population at risk before a heart attack happens.

Donations Open December 26th

33%

of heart attacks in people of South Asian descent occur under age 45

40 secs

Every 40 seconds, someone in the U.S. has a heart attack

400%

People of South Asian descent have 4x the risk of atherosclerosis

A Better Way

You are wondering if there is a better option. The heart calcium scan is a test that identifies heart disease and also helps cardiologists understand the likelihood of a heart attack in the next 5-10 years.

You can learn more about the heart calcium scan here

The Challenge

Investigators have generated data on the patterns of heart calcium scan results in South Asians. However, at present, the guidelines on when to get a heart calcium scan do not account for people of South Asian descent. If we can determine at what age someone should get a heart calcium scan, we can optimize health care resource use to identify population at risk before a heart attack happens.

How Your Support Changes Everything

The funds from this campaign will enable us to understand the role our DNA plays in heart disease risk for people of South Asian descent.

1. Donate

You join the mission by donating to this campaign.

2. Collect Data

A partnering non-profit startup collects salivary samples, and extracts and sequences DNA of participants in an established cohort of South Asians. We will use the funds raised to apply fancy math to calculate DNA-based predisposition for heart disease for each participant.

3. Analyze

Using DNA data and heart scans, we will create an initial model on recommended age people of South Asian descent should obtain a heart scan to identify heart disease before a heart attack occurs.

4. Scale

With this new model, we apply for large grants to study even more South Asians.

5. Certify

Armed with an algorithm improved by a larger data set, we apply to the Food and Drug Administration (FDA) for approval to use the algorithm, enabling physicians to obtain screening heart calcium scans at the right age in people of South Asian descent.

Advacing South Asian health

Ankur Kalra, MD

Ankur Kalra, MD

CEO @ makeadent.org
Saravanan Krishnamoorthy, MD

Saravanan Krishnamoorthy, MD

President @ TrineOMICS
Greg Gibson, Ph.D.

Greg Gibson, Ph.D.

Professor of Biology @ Georgia Tech

Let’s revolutionize South Asian heart health

Add your tax-deductible contribution starting December 26th!

Our budget to do this research study is $75,000

Donations Open December 26th